Sign, symptoms, diagnosis & treatment of Waldenstrom macroglobulinemia (WM)
What is Waldenstrom macroglobulinemia (WM) ?
Waldenstrom macroglobulinemia (WM) is a type of non-Hodgkin lymphoma (NHL). The cancer cells make large amount of abnormal protein called microglobulin. Waldenstrom macroglobulinemia is also called as lymphoplasmacystic lymphoma. Waldenstrom macroglobulinemia (WM) starts in the B cells. WM cells have features of both plasma cells and lymphocytes and are called lymphoplasmacytoid. The WM cells grows in the bone marrow and overcomes the normal cells thereby causing no resistance to infections or any kind of attack on the body. These cells then spread to other organs of the body and grow in liver, spleen, etc leading to abdominal pain.
Risk factors for Waldenstrom macroglobulinemia (WM)
- Exposure to x-ray before birth.
- Exposure to radiation.
- Past treatment with chemotherapy.
- Genetic conditions like down syndrome, neurofibromatosis type 1, bloom syndrome, fanconi anemia, ataxia telangiectasia, li-fraumeni syndrome.
- Certain changes in chromosomes or genes.
Waldenstrom macroglobulinemia (WM) symptoms
- Repeated infection
- Increased bruising and bleeding
- Bone pain
- Swollen tender gum
- Skin rashes
- Enlarged lymph glands
- Chest pains
Diagnosis of Waldenstrom macroglobulinemia (WM)
- Physical examination and history.
- Complete blood count with differential.
- Blood chemistry studies.
- Bone marrow aspiration and biopsy.
- Cytogenetic analysis.
- Lumbar puncture.
- Chest X-ray
Treatment of Waldenstrom macroglobulinemia (WM)
Although treatment of ALL depends on lot of factors like age, time of diagnosis and its type, however Bone marrow stem cell transplant is among the best options.
Best hospitals for Waldenstrom macroglobulinemia treatment in India
- BLK Superspecialty Hospital, New Delhi
- Artemis Hospital, Gurgaon
- Mazumdar Shaw Cancer Center, Bangalore
- HCG EKO Cancer Cneter, Kolkata
- American Oncology, Hyderabad
- Gleneagles Global Health City, Chennai
- Gleneagles Global BGS, Bangalore
- Continental Hospital, Hyderabad
- Yashoda Hospital, Hyderabad
- Seven Hills, Mumbai
Cost of treatment Waldenstrom macroglobulinemia (WM) treatment in India
Cost of treatment for ALL vary from hospital to hospital India. It also varies on time of diagnosis and its symptoms. The total cost may vary between $ 25000 USD up to $ 75,000 USD depending up to the treatment required.
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